3. Certain Antidepressants
Some antidepressants, particularly those that influence norepinephrine levels, can raise blood pressure by affecting the nervous system’s regulation of vascular tone. This includes certain types of serotonin-norepinephrine reuptake inhibitors (SNRIs) and tricyclic antidepressants.
While these medications are essential for managing depression and other mental health conditions, blood pressure monitoring is important when initiating or adjusting doses. Never discontinue antidepressants without consulting your prescriber, as abrupt cessation can have serious consequences.
4. Hormonal Birth Control
Certain hormonal contraceptives, especially those containing estrogen, can increase blood pressure in some individuals. The risk is higher in people over 35, those who are overweight, or smokers.
If you have hypertension, a healthcare professional can help select a contraceptive method that minimizes blood pressure impact. In some cases, non-hormonal options or progestin-only formulations may be preferable.
5. Herbal Supplements
Herbal supplements are often perceived as safe, but many can raise blood pressure or interfere with antihypertensive medications. Examples include licorice, ginseng, bitter orange, guarana, St. John’s wort, and ephedra (ma-huang).
Because supplements are not always disclosed during medical visits, it is important to inform your healthcare provider about every supplement you take to avoid potential interactions or adverse effects on blood pressure.


